IGF-1 LR3

IGF-1 LR3 (Insulin-Like Growth Factor-1 Long Arg3)

For Research Use Only. Not for Human or Veterinary Consumption.

IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 with an extended amino acid sequence that enhances its half-life and receptor binding affinity. It is commonly used in laboratory research to study cellular growth signaling, receptor interactions, and anabolic pathways. Researchers explore IGF-1 LR3 for its role in tissue regeneration, metabolic regulation, and cellular proliferation within controlled experimental models.

This compound is provided solely for qualified laboratory research. Not intended for therapeutic, diagnostic, or human use.

Mechanism of Action

• IGF-1 receptor agonist: Binds to IGF-1 receptors on muscle, bone, and connective tissue, activating growth and repair signaling.

• Anabolic stimulation: Increases protein synthesis, muscle cell proliferation, and myoblast differentiation.

• Enhanced glucose utilization: Improves insulin sensitivity and cellular glucose uptake.

• Long-acting form: Modified with an arginine substitution at position 3 and a 13-amino-acid extension to resist deactivation, with a half-life of ~20–30 hours (vs. ~20 minutes for native IGF-1).